@import url('https://fonts.googleapis.com/css2?family=DM+Sans:wght@400;500;600;700&family=Manrope:wght@400;500;600;700;800&display=swap');
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p{display:none}.article-rail a{border:none;margin:0!important}.article-rail h3{font-size:17px;margin:0}footer{display:block}footer>div{margin-top:25px}}@media(max-width:560px){.topline{font-size:8px;letter-spacing:.03em}.topline a{max-width:125px;text-align:right}.masthead{padding-block:24px}.brand{font-size:30px}.brand span{font-size:8px}.header-note{display:none}nav a{font-size:12px}main{padding-bottom:45px}.edition-bar{font-size:8px;gap:15px}.hero{display:flex;flex-direction:column}.hero h1{font-size:clamp(35px,9vw,44px)}.hero>div:first-child{padding:30px 0 15px}.hero p{font-size:14px}.hero-art{min-height:280px;margin-top:-15px;z-index:-1}.art-caption{left:0;bottom:20px}.orb-label{top:30px}.hero-art img{width:85%;right:0}.button{margin-top:23px;padding:13px 20px}.lead-grid{grid-template-columns:1fr}.lead-grid>article{padding:25px 20px}.lead-grid>article:first-child{padding:20px 0}.lead-grid h2{font-size:37px}.story-grid{grid-template-columns:1fr;gap:30px}.story-card h3{font-size:27px}.story-card p{font-size:14px}.directory-feature{grid-template-columns:1fr;margin-top:40px;padding:25px;gap:10px}.directory-feature h2{font-size:37px}.sample-dossier{transform:rotate(-2deg);margin:20px 0 5px}.stage-strip{display:grid;grid-template-columns:1fr 1fr;gap:25px}.stage-strip i{display:none}.stage-strip b{font-size:19px}.section-heading h2,.section-heading{font-size:24px}.section-heading a{font-size:10px}.page-intro{padding-top:35px}.page-intro h1{font-size:46px}.page-intro p{font-size:15px}.metrics b{font-size:32px}.metrics span{font-size:10px;padding-right:10px}.notice{padding:18px;font-size:12px}.provider-grid{grid-template-columns:1fr}.provider-card h3{font-size:29px}.provider-card p{font-size:13px}.dossier-layout{grid-template-columns:1fr;gap:25px}.dossier-summary{position:static}.dossier-summary ul{display:grid;grid-template-columns:1fr 1fr;gap:10px}.dossier-field p{font-size:14px}.timeline-item{grid-template-columns:1fr;gap:10px}.timeline-item h3{font-size:24px}.article-head h1{font-size:38px}.article-head>p{font-size:17px}.article-rail{display:block}.article-rail a{padding:10px 0}.prose{font-size:15px}.implication{padding:22px}.implication p{font-size:22px}.voices,.desks,.gap-grid{grid-template-columns:1fr}.voice p{max-width:100%}.source-index summary{font-size:12px}.source-index summary small{font-size:10px}.search{padding:23px 0}}

/* Support pages keep the same editorial rhythm, with a usable accessible contact form. */
.policy-date{font-size:.85rem;color:var(--muted);border-bottom:1px solid var(--line);padding-bottom:1.2rem}
.footer-links{display:flex;flex-wrap:wrap;gap:.45rem;max-width:44rem;font-size:.9rem}
.contact-layout{display:grid;grid-template-columns:1fr 1fr;gap:4rem;margin-bottom:5rem}
.contact-layout .prose{max-width:none;margin:0}
.contact-form{padding:2rem;background:#edf0e6;border:1px solid var(--line);align-self:start;display:grid;gap:.7rem}
.contact-form label{font-weight:600;margin-top:.4rem}
.contact-form input,.contact-form select,.contact-form textarea{width:100%;padding:.9rem;border:1px solid #829693;border-radius:0;font:inherit;background:var(--paper);color:var(--ink)}
.contact-form textarea{resize:vertical;min-height:10rem}
.contact-form small{color:var(--muted);line-height:1.6}
.contact-form .button{margin-top:1rem;cursor:pointer;font:inherit;border:1px solid var(--ink)}
.contact-form :focus-visible{outline:3px solid var(--ink);outline-offset:3px}
@media(max-width:760px){.contact-layout{grid-template-columns:1fr;gap:2rem}.contact-form{padding:1.25rem}.footer-links{line-height:1.8}}

/* Annual audit: actual corpus data, not decorative market metrics. */
.audit-panel{display:grid;grid-template-columns:1fr 1.2fr;gap:48px;padding:40px;background:#edf0e9;border:1px solid #d8ded3;margin:48px 0}.audit-panel h2{font-size:32px;line-height:1.15;margin:16px 0}.audit-panel p{line-height:1.65}.audit-bars{display:grid;gap:9px}.audit-bar-row{display:grid;grid-template-columns:144px 1fr 20px;align-items:center;gap:12px;font-size:12px}.audit-bar-row i{height:16px;background:linear-gradient(to right,#315d51 var(--bar),#d8ded3 var(--bar));border-radius:2px}.audit-bar-row b{font-weight:500}.audit-documents{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px;margin:32px 0}.audit-documents article{padding:24px;border:1px solid #d8ded3}.audit-documents a{font-size:14px;color:#315d51}.audit-documents p{line-height:1.65;font-size:14px}@media(max-width:700px){.audit-panel{grid-template-columns:1fr;padding:22px;gap:24px}.audit-documents{grid-template-columns:1fr}.audit-bar-row{grid-template-columns:128px 1fr 18px;gap:8px}}

/* Trial register: source fields and editorial judgment stay visibly distinct. */
.registry-intro{display:grid;grid-template-columns:1fr 1fr;gap:3rem;margin:3rem 0}.registry-intro h2{font-family:var(--serif,Georgia,serif);font-size:2.4rem;line-height:1.12;margin:.7rem 0 1.3rem}.registry-query-panel{background:#e9eee8;padding:2rem}.registry-query-panel h2{font-size:1.6rem}.registry-query-panel ul{padding:0;list-style:none}.registry-query-panel li{display:flex;flex-wrap:wrap;justify-content:space-between;gap:.4rem;padding:.65rem 0;border-bottom:1px solid #ccd5cb}.registry-query-panel li span{font-size:.75rem;color:#46564b}.registry-card{border-top:1px solid #bbc7ba;padding:2rem 0;overflow-wrap:anywhere}.registry-meta{display:flex;justify-content:space-between;gap:1rem;flex-wrap:wrap;font-size:.65rem;letter-spacing:.1em}.registry-card h2{font-family:var(--serif,Georgia,serif);font-size:1.7rem;line-height:1.2;max-width:54rem;margin:.8rem 0}.registry-id{font-size:.8rem;color:#526255}.registry-facts{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:1.1rem;margin:1.5rem 0}.registry-facts dt{font-size:.65rem;text-transform:uppercase;letter-spacing:.08em;color:#657367}.registry-facts dd{margin:.3rem 0 0;font-size:.9rem}.screening-note{background:#f0eee4;border-left:3px solid #8e9b71;padding:1rem 1.3rem;margin:1.4rem 0}.screening-note p{margin:.5rem 0 0;max-width:65rem}.registry-card details{background:#f5f5ef;padding:1rem 1.3rem}.registry-card summary{cursor:pointer;font-size:.8rem;font-weight:600}.registry-card details p{white-space:pre-line;max-width:65rem}.registry-card pre{white-space:pre-wrap;font-size:.75rem;overflow-wrap:anywhere}.registry-list [hidden]{display:none!important}
@media(max-width:700px){.registry-intro{grid-template-columns:1fr;gap:1.5rem}.registry-query-panel{padding:1.2rem}.registry-facts{grid-template-columns:repeat(2,minmax(0,1fr))}.registry-card h2{font-size:1.4rem}.registry-meta{letter-spacing:.05em}.registry-intro h2{font-size:2rem}}

/* Clinical evidence: within-trial comparisons; independent endpoint scales. */
.clinical-panel{display:grid;grid-template-columns:1fr 1fr;gap:3rem;padding:3rem 0;border-top:1px solid var(--line,#d7dcd5)}
.clinical-panel h2{font-size:clamp(2rem,4vw,3.6rem);line-height:1.05;margin:.7rem 0 1rem}.clinical-panel p{line-height:1.65}.clinical-facts{display:grid;grid-template-columns:6rem 1fr;gap:.7rem;margin:1.5rem 0}.clinical-facts dt{font-size:.75rem;text-transform:uppercase;letter-spacing:.08em}.clinical-facts dd{margin:0}.clinical-limit,.clinical-scale{font-size:.88rem;color:#48594e}.clinical-bars{margin:1.7rem 0}.clinical-row{display:grid;grid-template-columns:1fr auto;gap:.6rem 1rem;margin:1.5rem 0}.clinical-row>span{font-size:.9rem}.clinical-row>b{grid-column:2;grid-row:1;font-variant-numeric:tabular-nums}.clinical-track{grid-column:1/-1;height:15px;background:#e0e7df;border-radius:3px;overflow:hidden}.clinical-track i{display:block;height:100%;background:#38614e;border-radius:3px}.clinical-source{font-size:.85rem}@media(max-width:700px){.clinical-panel{grid-template-columns:1fr;gap:1.3rem;padding:2rem 0}.clinical-panel h2{font-size:2.3rem}.clinical-facts{grid-template-columns:5rem 1fr}.clinical-row>span{max-width:220px}}

.analytics-consent{position:fixed;z-index:100;bottom:1rem;left:1rem;right:1rem;max-width:44rem;margin:auto;padding:1.2rem;background:#fffaf3;color:#182d29;border:1px solid #71877c;box-shadow:0 8px 40px #183b3433;border-radius:8px}.analytics-consent p{margin:0 0 1rem}.analytics-consent button,.analytics-preferences{font:inherit;cursor:pointer;border:1px solid currentColor;border-radius:4px;padding:.5rem .75rem;margin:.25rem;background:transparent;color:inherit}.analytics-consent a{margin:.5rem;display:inline-block}.analytics-consent button:focus-visible,.analytics-preferences:focus-visible{outline:3px solid #a8772d;outline-offset:3px}

.source-note{font-size:12px;color:var(--muted);border-block:1px solid var(--line);padding:12px 0;max-width:850px}.source-note summary{cursor:pointer;font-weight:500}.source-note p{padding-top:12px}.source-note a{text-decoration:underline}

/* Newsletter — restrained editorial invitation, not an interruptive full-screen takeover. */
.newsletter-modal{color:var(--ink,#173e3b);background:#f8f7ee;border:1px solid #a8b3a4;padding:clamp(24px,5vw,48px);width:min(560px,calc(100% - 32px));max-height:90dvh;overflow:auto;box-shadow:0 20px 80px #102e2c38}.newsletter-modal::backdrop{background:#102e2c80;backdrop-filter:blur(3px)}.newsletter-modal h2{font-size:clamp(30px,5vw,44px);line-height:1.1;font-weight:500;margin:18px 0}.newsletter-modal>p{line-height:1.6}.newsletter-close{position:absolute;right:14px;top:10px;border:0;background:transparent;color:inherit;font-size:30px;cursor:pointer;width:40px;height:40px}.newsletter-form{display:grid;gap:12px;margin-top:25px}.newsletter-form>input[type=email]{width:100%;padding:14px;border:1px solid #879b91;background:#fffdf7;font:inherit;color:inherit;border-radius:0;box-sizing:border-box}.newsletter-form .newsletter-consent{display:flex;align-items:flex-start;gap:10px;font-size:13px;line-height:1.6;letter-spacing:0;text-transform:none}.newsletter-consent input{width:18px;height:18px;flex-shrink:0;margin:2px 0}.newsletter-form button.button{border:0;font:inherit;cursor:pointer;width:100%;justify-content:space-between}.newsletter-form button:disabled{opacity:.55;cursor:default}.newsletter-status{font-size:13px;line-height:1.6;margin:0;min-height:22px}.newsletter-later{background:none;border:0;text-decoration:underline;color:inherit;padding:12px 0 0;cursor:pointer;font:inherit}.newsletter-panel{border:1px solid #ccd3c5;background:#f2f2e7;padding:32px;align-self:start}.newsletter-trap{position:absolute!important;left:-10000px!important;width:1px;height:1px;overflow:hidden}.newsletter-modal button:focus-visible,.newsletter-form input:focus-visible,.newsletter-form a:focus-visible{outline:3px solid #587b63;outline-offset:3px}@media(max-width:600px){.newsletter-panel{padding:20px}.newsletter-modal{padding:30px 22px}}